肖 琦
学历、职称:博士、教授、研究员/博士生导师(分析化学)、硕士生导师(分析化学、物理化学、学科教学(化学))
职务:南宁师范大学校长助理、科研管理处处长
社会兼职:中国化工学会专家库专家、第六届中国青年科技工作者协会理事会理事、教育部师范专业认证专家、中国化学会化学热力学与热分析专业委员会委员、广西工会第十三次代表大会代表、广西化学化工学会常务理事、副理事长、广西欧美同学会(广西留学人员联谊会)第六届理事会理事、广西武汉大学校友会理事、中国化学会会员、中国化工学会会员、中国毒理学会会员、广西高校科研实验室建设及安全管理专家委员会委员、南宁师范大学教学指导委员会委员、工会第八届委员会委员、南宁师范大学学术委员会科学研究专委会委员、西南大学博士生导师。
研究方向:①纳米材料生物效应;
②小分子与生物大分子相互作用机制;
③生命电分析化学;
④纳米生物传感器。
Email:qi.xiao@nnnu.edu.cn
教育与研究经历
2001.9-2005.7 武汉大学应用化学专业,获理学学士学位;
2005.9-2010.7 武汉大学物理化学专业,获理学博士学位(硕博连读);
2009.7-2010.8 香港浸会大学化学系交流博士生;
2010.8-2011.10 美国马萨诸塞大学化学系,博士后;
2011年10月至今 南宁师范大学化学与材料学院,副教授(2012年),硕士生导师(2013年),研究员(2014年),博士生导师(2016年) ,教授(2020年)。
长期从事新型低毒量子点等纳米材料制备及其生物效应,抗肿瘤药物小分子与生物大分子相互作用机制及生命电分析化学研究。以第一作者或通讯作者在Biosens. Bioelectron.,J. Hazard. Mater.,Sensor. Actuat. B: Chem.,Anal. Chem.,Chem. Commun.等国内外学术期刊发表论文80多篇,中科院一区论文24篇,二区论文30篇,被30 多个国家的同行在Science, Nat. Nanotechnol., Chem. Rev. , Chem. Soc. Rev., J. Am. Chem. Soc.等国际顶级学术期刊正面评价和引用超过2000次。相关研究成果获授权国家发明专利68件,转让50余件。受邀为Nanoscale, Biosens. Bioelectron., Carbon等40多种国际学术期刊评审相关稿件。目前主持和参与国家和省部级项目10余项。2014年入选广西高等学校优秀中青年骨干教师培养工程第二期培养对象。2017年入选广西高等学校高水平创新团队及卓越学者计划。获得广西自然科学奖三等奖2项。
教学情况
主讲本科生基础课《物理化学》、《结构化学》和专业选修课《科学研究方法概论》;研究生学位课《材料化学》和《现代电分析化学》。指导研究生获得自治区级研究生创新项目3项,指导研究生获得国家奖学金8人,自治区优秀毕业研究生2人;指导本科生获得 国际“互联网+”大学生创新创业大赛铜奖1项、广西赛区金银铜奖各1项,广西高校大学生化学化工类论文及设计竞赛一等奖2项、二等奖2项、三等奖1项,获得国家大学生创新创业训练计划项目4项和广西大学生创新创业训练计划项目4项,获得 “挑战杯”广西大学生课外学术科技作品竞赛二等奖和三等奖各1项。获广西高等教育自治区级教学成果奖二等奖2项。作为负责人的专业入选国家级一流本科专业建设点,作为负责人的课程获认定为国家级一流本科课程。
获奖及荣誉称号
1、2022年自治区优秀教育工作者
2、2022年第九届广西青年学术年会论文三等奖(排名第一)
3、2021年广西高等教育自治区级教学成果二等奖(排名第二)
4、2015-2020年南宁师范大学先进工作者
5、2021年南宁师范大学优秀共产党员
6、2020年广西科学技术奖自然科学类三等奖(第一完成人)
7、2019年第八届广西青年学术年会论文二等奖(排名第一)
8、2019年广西高等教育自治区级教学成果二等奖(排名第二)
9、2018年广西五一劳动奖章
10、2018年广西青年五四奖章
11、2017年广西科学技术奖自然科学类三等奖(第一完成人)
12、2017年第十四届广西青年科技奖
13、2017年广西自然科学基金-杰出青年基金获得者
14、2017年广西高等学校卓越学者
15、2016年广西师范学院优秀共产党员
16、2015年广西师范学院科研管理工作先进个人
17、2014-2015学年度广西师范学院教学管理先进个人
18、2012-2015学年度广西师范学院“三育人”先进个人
19、2014年度广西师范学院“优秀班主任”
20、2013年度广西师范学院“优秀班主任”
承担项目与课题
(1) 国家自然科学基金地区基金项目,“线粒体作为氧化石墨烯生物效应作用靶点的热力学诠释及其分子机制研究”。
(2) 国家自然科学基金地区基金项目,“基于生物热力学方法的功能化氧化石墨烯与蛋白质相互作用机制研究”。
(3)国家自然科学基金青年基金项目,“系列表面功能化量子点与线粒体相互作用机理研究”。
(4) 广西自然科学基金杰出青年基金项目,“生物热化学”。
(5) 广西高等学校高水平创新团队及卓越学者,“量子点生物效应物理化学基础”。
(6) 广西自然科学基金青年基金项目,“基于生物热力学方法的I-VI型近红外发光量子点与蛋白质相互作用机制研究”。
(7) 广西自然科学基金回国基金项目,“系列表面功能化量子点对线粒体功能影响的热力学及其分子机制研究”。
(8) 广西高校科研项目重点项目,“基于化学热力学的新型功能化量子点生物效应检测技术”。
(9) 病毒学国家重点实验室开放课题,“基于荧光纳米量子点探针的细小病毒-细胞相互作用机制研究”。
(10) 广西高等学校优秀中青年骨干教师培养工程。
主要学术论文(* 通讯作者)
2023年
1. Zhipeng Chen, Lei Yang, Wenju Xu, Feifei Xu, Jiarong Sheng*, Qi Xiao*, Xiangzhi Song, Wenqiang Chen*. Homoadamantane-Fused Tetrahydroquinoxaline as a Robust Electron-Donating Unit for High-Performance Asymmetric NIR Rhodamine Development. Analytical Chemistry 2023, 95, 3325−3331.
2. Qi Xiao*, Huajian Luo, Huishan Cao, Bo Li, Jiajia Liu, Yi Liu, Shan Huang*. Investigation on conformational variation and enzymatic activity of trypsin affected by Ti3C2 QDs via spectroscopic technique and molecular modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2023, 285, 121878.
3. Jiajia Liu, Bo Li, Lingxin Kong, Qi Xiao*, Shan Huang*. Surfactants-assisted morphological regulation of BiVO4 nanostructures for photocatalytic degradation of organic pollutants in wastewater. Journal of Physics and Chemistry of Solids 2023, 172, 111079.
4. Rukui Zhu, Yu Liang, Huajian Luo, Huishan Cao, Yi Liu, Shan Huang*, Qi Xiao*. Investigations of interaction mechanism and conformational variation of serum albumin affected by artemisinin and dihydroartemisinin. Journal of Molecular Recognition 2023, 34, e2876.
5. Qi Xiao*, Xincong Tu, Huishan Cao, Huajian Luo, Bo Li, Jiajia Liu, Yi Liu, Shan Huang*. Interaction thermodynamics investigation of bovine serum albumin with black phosphorus quantum dots via spectroscopic and molecular simulation techniques. Journal of Molecular Structure 2023, 1276, 134725.
6. Yali Wang, Shuai Liu, Dongyou Zhang, Qi Xiao*, Shan Huang*. Ultrasensitive electrochemical platform for p53 gene via molecular beacon-mediated circular strand displacement and terminal deoxynucleotidyl transferase-mediated signal amplification strategy. Analyst 2023, 147, 2412−2424.
2022年
1. Gan Ning, Pingping Mu, Bo Li, Jiajia Liu, Qi Xiao*, Shang Huang*. Fluorine and nitrogen co-doped near-infrared carbon dots for fluorescence “on-off-on” determination of nitrite. Microchimica Acta 2022, 189, 230.
2. Gan Ning, Bo Li, Jiajia Liu, Qi Xiao*, Shang Huang*. Red‑emission carbon dots as fluorescent “on-off-on” probe for highly sensitive and selective detection of Cu2+ and glutathione. Analytical and Bioanalytical Chemistry 2022, 414, 2219−2233.
3. Shan Huang*, Jiandong Yao, Gan Ning, Bo Li, Pingping Mu, Qi Xiao*. Ultrasensitive ratiometric fluorescent probe for Hg(II) and trypsin activity based on carbon dots and metalloporphyrin via target recycling amplification strategy. Analyst 2022, 147, 1457−1466.
4. Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao*, Shan Huang*. A label-free and ultrasensitive electrochemical biosensor for oral cancer overexpressed 1 gene via exonuclease III-assisted target recycling and dual enzymes-assisted signal amplification strategies. Analyst 2022, 147, 2412−2424.
5. Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao*, Shan Huang*. Ultrasensitive electrochemical biosensor for HPV16 oncogene based on Y-shaped DNA catalytic hairpin assembly and template-free DNA extension reaction. Electroanalysis 2022, 34, 1001−1011.
2021年
1. Huajian Luo, Bo Li, Jiajia Liu, Yi Liu, Qi Xiao*, Shang Huang*. Investigation on conformational variation and fibrillation of human serum albumin affected by molybdenum disulfide quantum dots. International Journal of Biological Macromolecules 2021, 190, 999−1006.
2. Junan Xiao*, Hai Peng, Jinshao Liang, Rufang Meng, Wei Su, Qi Xiao*, Hua Yang*. Gold/scandium bimetallic relay catalysis of formal [5+2]- and [4+2]-annulations: access to tetracyclicindole scaffolds. Chemical Communications 2021, 57, 13369−13372.
3. Shan Huang, Jiandong Yao, Bo Li, Gan Ning, Qi Xiao*. Integrating target-responsive CD-CdTe QD-based ratiometric fluorescence hydrogel with smartphone for visual and on-site determination of dichlorvos. Microchimica Acta 2021, 188, 318.
4. Huajian Luo, Haimei Li, Yi Liu, Liyun Yang, Qi Xiao*, Shan Huang*. Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2021, 256, 119746.
5. Shan Huang*, Xiaoyu Jin, Dongyou Zhang, Yali Wang, Dan Wang, Qi Xiao**, Wenxi Zhang. Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of p53 gene based on nicking endonuclease-assisted target recycling and rolling circle amplification. Microchemical Journal 2021, 168, 106461.
6. Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao*, Shan Huang*. Ultrasensitive electrochemical biosensor for HPV16 oncogene based on Y-shaped DNA catalytic hairpin assembly and template-free DNA extension reaction. Electroanalysis 2021, 51, 74−84.
7. Huajian Luo, Yu Liang, Huiying Zhang, Yi Liu, Qi Xiao*, Shan Huang*. Comparison on binding interactions of quercetin and its metal complexes with calf thymus DNA by spectroscopic techniques and viscosity measurement. Journal of Molecular Recognition 2021, 34, e2933.
8. 黄珊, 姚建东, 宁淦, 肖琦*, 刘义. 石墨烯量子点荧光探针对碱性磷酸酶活性的高效检测. 高等学校化学学报 2021, 42, 2412−2421.
9. 罗华健, 李海梅, 肖琦, 黄珊*, 刘义*. 三种不同元素掺杂的碳点与DNA相互作用及其机制研究. 中国科学:化学 2021, 51, 74−84.
2020年
1. Jiali Liu, Jie Jiang, Jiaqi Zhang, Yaqin Chai, Qi Xiao*, Ruo Yuan*. The Combination of Ternary Electrochemiluminescence System of g-C3N4 Nanosheet/TEA/Cu@Cu2O and G-quadruplex-Driven Regeneration Strategy for Ultrasensitive Bioanalysis. Biosensors and Bioelectronics 2020, 152, 112006.
2. Shan Huang, Haimei Li, Yi Liu, Liyun Yang, Dan Wang, Qi Xiao*. Investigations of conformational structure and enzymatic activity of trypsin after its binding interaction with graphene oxide. Journal of Hazardous Materials 2020, 392, 122285.
3. Xinghua Li, Ting Huang, Ying Song, Yue Qi, Limin Li, Yanping Li, Qi Xiao*, Yuanfei Zhang*. Co(III)-Catalyzed Annulative Vinylene Transfer via C-H Activation: Three-Step Total Synthesis of 8-Oxopseudopalmatine and Oxopalmatine. Organic Letters 2020, 22, 5925−5930.
4. Shan Huang, Jiandong Yao, Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*. A ratiometric fluorescent assay for evaluation of alkaline phosphatase activity based on ionic liquid–functionalized carbon dots. Microchimica Acta 2020, 187, 271.
5. Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*, Shan Huang*. Bright Mn-doped carbon dots for the determination of permanganate and L-ascorbic acid by a fluorescence on-off-on strategy. Microchimica Acta 2020, 187, 659.
6. Shan Huang, Haimei Li, Huajian Luo, Liyun Yang, Zhiqiang Zhou, Qi Xiao*, Yi Liu*. Conformational structure variation of human serum albumin after binding interaction with black phosphorus quantum dots. International Journal of Biological Macromolecules 2020, 146, 405−414.
7. Zhiqiang Zhou, LiyunYang*, Ling Huang, Yuanping Liao, Yi Liu, Qi Xiao*. A novel fluorescent probe for H2O2 detection based on CdSe@ZnS quantum dots/Ag nanocluster hybrid. Analytica Chimica Acta 2020, 1106, 176−182.
8. Qi Xiao, Jiandan Liang, Huajian Luo, Haimei Li, Jing Yang, Shan Huang*. Investigations of conformational structures and activities of trypsin and pepsin affected by food colourant allura red. Journal of Molecular Liquids 2020, 319, 114359.
9. Shan Huang, Huajian Luo, Yi Liu, Wei Su, Qi Xiao*. Comparable investigation of binding interactions between three arene ruthenium(II) thiosemicarbazone complexes and calf thymus DNA. Polyhedron 2020, 192, 114864.
10. Zhiqiang Zhou, Liyun Yang*, Yuanping Liao, Huiyan Wu, Xiaohui Zhou, Shan Huang, Yi Liu, Qi Xiao*. Mn:ZnSe quantum dots-based turn-on fluorescent sensor for highly selective and sensitive detection of Cd2+. Analytical Methods 2020, 12, 552−556.
2019年
1. Zihua Wu*, Yuling Liang, Linqi Cao, Qing Guo, Suju Jiang, Fangfang Mao, Jiarong Sheng, Qi Xiao*. High-yield synthesis of monodisperse gold nanorods with a tunable plasmon wavelength using 3-aminophenol as the reducing agent. Nanoscale 2019, 11, 22890−22898.
2. Qi Xiao*, Jiawen Li, Xiaoyu Jin, Yi Liu, Shan Huang*. Ultrasensitive electrochemical microRNA-21 biosensor coupling with carboxylate-reduced graphene oxide-based signal-enhancing and duplex-specific nuclease-assisted target recycling. Sensors and Actuators B: Chemical 2019, 297, 126740.
3. Shan Huang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*, Yue Zhang*. One-step facile synthesis of nitrogen-doped carbon dots: A ratiometric fluorescent probe for evaluation of acetylcholinesterase activity and detection of organophosphorus pesticides in tap water and food. Journal of Agricultural and Food Chemistry 2019, 67, 11244−11255.
4. Qi Xiao, Jinrong Feng, Mengmeng Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. A ratiometric electrochemical aptasensor for ultrasensitive determination of adenosine triphosphate via triple-helix molecular switch. Microchimica Acta 2019, 186, 478.
5. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*. Nitrogen, phosphorus and sulfur tri-doped carbon dots are specific and sensitive fluorescent probes for determination of chromium(VI) in waters samples and in living cells. Microchimica Acta 2019, 186, 851.
6. Qi Xiao, Jinrong Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of K-ras gene via exonuclease III-assisted target recycling and rolling circle amplification strategies. Analytical Methods 2019, 11, 4146−4156.
7. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Yue Zhang, Qi Xiao*. Nitrogen, cobalt co-doped magnetic carbon dots as a ratiometric fluorescence universal platform for cholesterol and uric acid in human blood serum. ACS Omega 2019, 4, 9333−9342.
8. Erli Yang, Jiandong Yao, Lumin Wang, Yi Liu, Qi Xiao, Shan Huang*. InP/ZnS quantum dot-based fluorescent probe for directly sensitive and selective detection of horseradish peroxidase. Methods and Applications in Fluorescence 2019, 7, 035008.
9. Shan Huang, Haimei Li, Yi Liu, Yu Liang, Wei Su, Qi Xiao*. Comparable investigation of in vitro interactions between three ruthenium(II) arene complexes with curcumin analogs and ctDNA. Polyhedron 2019, 167, 51−61.
2018年
1. Yuanyuan Chang, Mengyao Li, Zhongyu Wu, Ying Zhuo, Yaqin Chai, Qi Xiao*, Ruo Yuan*. Homogeneous Entropy Catalytic-Driven DNA Hydrogel as Strong Signal Blocker for Highly Sensitive Electrochemical Detection of Platelet-Derived Growth Factor. Analytical Chemistry 2018, 90, 8241−8247.
2. Shan Huang, Erli Yang, Yi Liu, Jiandong Yao, Wei Su, Qi Xiao*. Low-temperature rapid synthesis of nitrogen and phosphorusdual-doped carbon dots for multicolor cellular imaging andhemoglobin probing in human blood. Sensors and Actuators B 2018, 265, 326−334.
3. Shan Huang, Mengmeng Feng, Jiawen Li, Yi Liu, Qi Xiao*. Voltammetric determination of attomolar levels of a sequence derived from the genom of hepatitis B virus by using molecular beacon mediated circular strand displacement and rolling circle amplificationr. Microchimica Acta 2018, 185, 206
4. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Carbon dots doped with nitrogen and boron as ultrasensitive fluorescent probes for determination of α-glucosidase activity and its inhibitors in water samples and living cells. Microchimica Acta 2018, 185, 394.
5. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Red emission nitrogen, boron, sulfur co-doped carbon dots for “on-off-on” fluorescent mode detection of Ag+ ions and L-cysteine in complex biological fluids and living cells. Analytica Chimica Acta 2018, 1035, 192−202.
6. Qi Xiao, Jinrong Feng, Jiawen Li, Mengmeng Feng, Shan Huang*. A label-free and ultrasensitive electrochemical aptasensor for lead(II) using a N,P dual-doped carbon dot-chitosan composite as a signal-enhancing platform and thionine as a signaling molecule. Analyst 2018, 143, 4764−4773.
7. Shan Huang, Erli Yang, Lumin Wang, Yi Liu, Jiangning Xie, Baoqing Hu, Qi Xiao*. Carbon dots-based frequency-doubling scattering probes for the ultrasensitive and highly selective determination of hemoglobin. Analytical Methods 2018, 10, 891−899.
8. Qi Xiao, Mengmeng Feng, Yi Liu, Shuangyan Lu, Yingzi He, Shan Huang*. The graphene/polypyrrole/chitosan-modified glassy carbon electrode for electrochemical nitrite detection. Ionics 2018, 24, 845−859.
9. Qi Xiao, Yu Liang, Yi Liu, Shuangyan Lu, Shan Huang*. Comparison of molecular interactions of Ag2Te and CdTe quantum dots with human serum albumin by spectroscopic approaches. Luminescence 2018, 33, 181−189.
10. Shan Huang, Yu Liang, Jianguo Cui*, Jiangning Xie, Yi Liu, Baoqing Hu, Qi Xiao**. Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer. Steroids 2018, 132, 46−55.
2017年
1.Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Label-free and ratiometric fluorescent nanosensor based on amino-functionalized graphene quantum dots coupling catalytic G-quadruplex/hemin DNAzyme for ultrasensitive recognition of human telomere DNA. Sensors and Actuators B 2017, 245, 648−655.
2. Qi Xiao, Yu Liang, Fawei Zhu, Shuangyan Lu, Shan Huang*. Microwave-assisted one-pot synthesis of highly luminescent N-doped carbon dots for cellular imaging and multi-ion probing. Microchim Acta 2017, 184, 2429–2438.
3. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shuyu Zhou, Jiarong Sheng, Shan Huang*. An electrochemical chiral sensor based on amino‑functionalized graphene quantum dots/β-cyclodextrin modified glassy carbon electrode for enantioselective detection of tryptophan isomers. Journal of the Iranian Chemical Society 2017, 14, 1957–1970.
4. Shan Huang, Jiangning Xie, Jianguo Cui*, Liang Liu, Yu Liang, Yi Liu, Qi Xiao**. Comparative investigation of binding interactions between three steroidal compounds and human serum albumin: Multispectroscopic and molecular modeling techniques. Steroids 2017, 128, 136–146.
5. Shan Huang, Jiangning Xie, Wei Su, Yi Liu, Xiaohui Wang, Baoqing Hu, Qi Xiao*. Comparative investigation of interactions between two ruthenium(II) arene PTA type complexes with curcuminoid ligands and human serum albumin. Journal of Organometallic Chemistry 2017, 853, 81–92.
2016年
1. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Lixia Zhang, Wei Su, Qi Xiao*. An electrochemical biosensor based on single-stranded DNA modified gold electrode for acrylamide determination. Sensors and Actuators B 2016, 224, 22–30.
2. Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Amino-functionalized graphene quantum dots based ratiometric fluorescent nanosensor for ultrasensitive and highly selective recognition of horseradish peroxidase. Sensors and Actuators B 2016, 234, 255–263.
3. Shan Huang, Shushu Peng, Wei Su, Zhaofeng Tang, Jianguo Cui, Chusheng Huang, Qi Xiao*. In vitro interaction investigation between three Ru(II) arene complexes and human serum albumin: Structural influences. RSC Advances 2016, 6, 47043–47054.
4. Shan Huang, Hangna Qiu, Jiangning Xie, Chusheng Huang, Wei Su, Baoqing Hu, Qi Xiao*. Systematical investigation of in vitro molecular interaction between fluorescent carbon dots and human serum albumin. RSC Advances 2016, 6, 44531–44542.
5. Shan Huang, Lumin Wang, Chusheng Huang, Baoqing Hu, Wei Su, Qi Xiao*. Graphene quantum dot coupled with gold nanoparticle based “off-on” fluorescent probe for sensitive and selective detection of L-cysteine. Microchimica Acta 2016, 183, 1855−1864.
6. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Jianguo Cui, Wei Su, Qi Xiao*. Systematical investigation of in vitro interaction of InP/ZnS quantum dots with human serum albumin by multispectroscopic approach. Colloids and Surfaces B 2016, 148, 165−172.
7. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shan Huang*. Novel N-doped carbon dots/β-cyclodextrin nanocomposites for enantioselective recognition of tryptophan enantiomers. Sensors 2016, 16, 1874.
8. Shan Huang, Shushu Peng, Fawei Zhu, Xiaolin Lei, Qi Xiao*, Wei Su, Yi Liu, Chushgeng Huang, Lixia Zhang. Multispectroscopic investigation of the interaction between two ruthenium(II) arene complexes of curcumin analogs and human serum albumin. Biological Trace Element Research 2016, 169, 189−203.
9. Shan Huang, Yu Liang, Chusheng Huang, Wei Su, Xiaolin Lei, Yi Liu, Qi Xiao*. Systematical investigation of binding interaction between novel ruthenium(II) arene complex with curcumin analogs and ctDNA. Luminescence 2016, 31, 1384−1394.
2015年
1. Shan Huang, Hangna Qiu, Shuangyan Lu, Fawei Zhu, Qi Xiao* Study on the molecular interaction of graphene quantum dots with human serum albumin: Combined spectroscopic and electrochemical approaches. Journal of Hazardous Materials 2015, 285, 18–26.
2. Shan Huang, Lumin Wang, Chusheng Huang, Jiangning Xie, Wei Su, Jiarong Sheng, Qi Xiao* A carbon dots based fluorescent probe for selective and sensitivedetection of hemoglobin. Sensors and Actuators B 2015, 221, 1215–1222.
3. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Wei Su, Qi Xiao*. Molecular interaction investigation between three CdTe:Zn2+ quantum dots and human serum albumin: A comparative study. Colloids and Surfaces B 2015, 136, 955–962.
4. Shan Huang, Hangna Qiu, Fawei Zhu, Shuangyan Lu, Qi Xiao*. Graphene quantum dots as on-off-on fluorescent probes for chromium(VI) and ascorbic acid. Microchimca Acta 2015, 182, 1723–1731.
5. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Wei Su, Lixia Zhang, Qi Xiao*. Sensitive and selective stripping voltammetric determination of copper(II) using a glassy carbon electrode modified with amino-reduced graphene oxide and β-cyclodextrin. Microchimica Acta 2015, 182, 2529–2539.
6. Shan Huang, Lumin Wang, Fawei Zhu, Wei Su, Jiarong Sheng, Chusheng Huang, Qi Xiao* A ratiometric nanosensor based on fluorescent carbon dots for label-free and highly selective recognition of DNA. RSC Advances 2015, 5, 44587–44597.
7. Shan Huang, Fawei Zhu, Qi Xiao*, Yu Liang, Quan Zhou, Wei Su*. Thermodynamic investigation of the interaction between the [(h6-p-cymene)Ru(benzaldehyde-N4-phenylthiosemicarbazone)Cl]Cl anticancer drug and ctDNA: multispectroscopic and electrochemical studies. RSC Advances 2015, 5, 42889–42902.
8. Shan Huang, Fawei Zhu, Quanquan Qian, Qi Xiao*, Wei Su*. Thermodynamic investigation of interaction between [(η6-p-Cymene)RuII(Acetone-N4- Phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin: Spectroscopic and electrochemical studies. Biological Trace Element Research 2015, 164, 150–161.
2014年
1. Shan Huang, Fawei Zhu, Qi Xiao*, Wei Su, Jiarong Sheng, Chusheng Huang, Baoqing Hu. A CdTe/CdS/ZnS core/shell/shell QDs-based "OFF-ON" fluorescent biosensor for sensitive and specific determination of L-ascorbic acid. RSC Advances 2014, 4, 46751–46761.
2. Shan Huang, Fawei Zhu, Qi Xiao*, Quan Zhou, Wei Su*, Hangna Qiu, Baoqing Hu, Jiarong Sheng, Chusheng Huang. Combined spectroscopy and cyclic voltammetry investigates the interaction between [(h6-p-cymene)Ru(benzaldehyde-N(4)-phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin. RSC Advances 2014, 4, 36286–36300.
3. Shan Huang, Fawei Zhu, Hangna Qiu, Qi Xiao*, Quan Zhou, Wei Su, Baoqing Hu. A Sensitive Quantum Dots-based “OFF-ON” Fluorescent Sensor for Ruthenium Anticancer Drugs and ctDNA. Colloids and Surfaces B 2014, 117, 240–247.
2013年
1. Qi Xiao, Shan Huang, Wei Su, Peiyuan Li, Jianqiang Ma, Fenping Luo, Jing Chen, Yi Liu. Systematically investigations of conformation and thermodynamics of HSA adsorbed to different sizes of CdTe quantum dots. Colloids and Surfaces B 2013, 102, 76–82.
2. Shan Huang, Qi Xiao*, Wei Su, Peiyuan Li, Jianqiang Ma, Zhike He. Simple and Sensitive Determination of Papain by Resonance Light-Scattering with CdSe Quantum Dots. Colloids and Surfaces B 2013, 102, 146–151.
3. Qi Xiao, Shan Huang, Wei Su, Peiyuan Li, Yi Liu. Evaluate the potential toxicity of quantum dots on bacterial metabolism by microcalorimetry. Thermochimica Acta 2013, 552, 98–105.
4. Qi Xiao, Hangna Qiu, Shan Huang, Chusheng Huang, Wei Su, Baoqing Hu, Yi Liu. Systematic Investigation of Interactions between Papain and MPA-capped CdTe Quantum Dots. Molecular Biology Reports 2013, 40, 5781–5789.
5. Shan Huang, Jianqiang Ma, Qi Xiao*, Mingyue Dong, Xuehua Li, QiulingLuo. Direct Determinaiton of Isocarbophos by using Oil Soluble CdSe Quantum Dots as Fluorescent Probe. Spectroscopy and Spectral Analysis 2013, 33, 2853–2857.
6. Shan Huang, Hangna Qiu, Qi Xiao*, Chusheng Huang, Wei Su, Baoqing Hu. A Simple QD–FRET Bioprobe for Sensitive and Specific Detection of Hepatitis B Virus DNA. Journal of Fluorescence 2013, 23, 1089–1098.
7. Ziqiang Xu,Liyun Yang,Xiaoyang Fan,Jiancheng Jin,Jie Mei,Wu Peng,Fenglei Jiang,Qi Xiao,Yi Liu*,Low temperature synthesis of highly stable phosphate functionalized two color carbon nanodots and their application in cell imaging. Carbon, 2013, 66, 351–360.
2012年
1. Qi Xiao, Shan Huang, Wei Su, WH Chan, Yi Liu. Facile synthesis and characterization of highly fluorescent and biocompatible N-acetyl-L-cysteine capped CdTe/CdS/ZnS core/shell/shell quantum dots in aqueous phase. Nanotechnology 2012, 23, 495717.
2. Qi Xiao, Shan Huang, Wei Su, Peiyuan Li, Yi Liu. Systematically Investigation of Interactions between BSA and Different Charge-capped CdSe/ZnS Quantum Dots. Journal of Photochemistry and Photobiology A: Chemistry 2012, 249, 53–60.
3. Qi Xiao, Shan Huang, Wei Su, Peiyuan Li, Yi Liu. Evaluate the potential environmental toxicity of quantum dots on ciliated protozoa by microcalorimetry. Thermochimica Acta 2012, 547, 62–69.
4. Qi Xiao, Ting Qiu, Shan Huang, Yi Liu, Zhike He. Preparation and Biological Effect of Nucleotide Capped CdSe/ZnS Quantum Dots on Tetrahymena Thermophila. Biological Trace Element Research 2012, 147, 346–353.
5. Qinglian Guo, Juan. Zhang, Ziqiang Xu, Ran Li, Fenglei Jiang, Qi Xiao*, Yi Liu. Comparative study on the effects of two antifungal drugs against Candida albicans by microcalorimetry and transmission electron microscopy. Thermochimica Acta 2012, 543, 82–87.
6. Xiaole Han, Lu Lai, Fangfang Tian, Fenglei Jiang, Qi Xiao, Yong Li, Qiuliyang Yu, Dongwei Li, Jia Wang, Qiumeng Zhang, Bofan Zhu, Ran Li, Yi Liu. Toxicity of CdTe Quantum Dots on Yeast Saccharomyces Cerevisiae. Small 2012, 8, 2680–2689.
2011年以前
1. Yong Lei, Qi Xiao , Shan Huang, Wansu Xu, Zhe Zhang, Zhike He, Yi Liu, Fengjiao Deng. Impact of CdSe/ZnS quantum dots on the development of zebrafish embryos. Journal of Nanoparticle Research 2011, 13, 6895–6906.
2. Qi Xiao, Shan Huang, Yushu Ge, Zhike He, Yi Liu, Jiangong Liang. A novel fluorescent silver ion biosensor based on nucleic acid molecular "light switch". Journal of Fluorescence 2010, 20, 541–549.
3. Qi Xiao, Bo Zhou, Shan Huang, Fangfang Tian, Hongliang Guan, Yushu Ge, Xiaorong Liu, Zhike He, Yi Liu. Direct Observation of the Binding Process between Protein and Quantum Dots by In-situ Surface Plasmon Resonance Measurements. Nanotechnology 2009, 20, 325101.
4. Qi Xiao, Shan Huang, Liu Yi, Fangfang Tian, Juncheng Zhu. Thermodynamics, Conformation and Active Sites of the Binding of Zn-Nd Hetero-bimetallic Schiff Base to Bovine Serum Albumin. Journal of Fluorescence 2009, 19, 317–326.
5. Shan Huang, Qi Xiao , Zhike He, Yi Liu, Philip Tinnefeld, Xiongrui Su, Xiaoniu Peng. A high sensitive and specific QDs FRET bioprobe for MNase. Chemical Communications 2008, 45, 5990–5992.
6. Qi Xiao, Shan Huang, Zude Qi, Bo Zhou, Zhike He, Liu Yi. Conformation, thermodynamics and stoichiometry of HSA adsorbed to colloidal CdSe/ZnS quantum dots. BBA-Proteins and Proteomics 2008, 1784, 1020–1027.