学历、职称：博士、教授，硕士生导师（分析化学、无机化学、学科教学（化学））
研究方向：多功能纳米光/电化学生物分析
兼职：中国化工学会专家库专家；广西化学化工学会理事；中国化学会会员；教育部博士/硕士学位论文评审专家；国家级及省级科技项目评审专家；南宁师范大学学术委员会委员
Email：huangs@nnnu.edu.cn
教育与研究经历
2000.09—2004.07 武汉大学应用化学专业，理学学士学位；
2004.09—2009.07 武汉大学分析化学专业，理学博士学位（硕博连读）；
2009.08—2011.10 加拿大魁北克大学国家科学研究院，博士后；
2018.07—2019.07 美国内布拉斯加大学林肯分校，访问学者，国家留学基金管理委员会西部地区人才培养特别项目；
2019.09—2020.01 武汉大学，访问学者，广西高等学校千名中青年骨干教师培育计划项目；
2010年07月至今 南宁师范大学化学与材料学院，硕士生导师（2013年），副教授（2016年），教授（2019年）。
教学情况
主讲《分析化学》、《仪器分析》、《分析化学实验》和《仪器分析实验》等本科生专业课，《现代分子光谱》和《生物分析化学》等研究生学位课。指导本科生获广西高校化学化工类论文及设计竞赛一等奖4项和二等奖4项、“挑战杯”广西大学生课外学术科技作品竞赛二等奖和三等奖各1项、“互联网+”大学生创新创业大赛广西赛区铜奖1项。指导本科生获国家级大学生创新创业计划项目8项、自治区级大学生创新创业计划项目4项。指导研究生获自治区级研究生创新项目3项、研究生国家奖学金7人、自治区优秀毕业研究生2人。主持完成广西高等教育本科教学改革工程项目一般A类项目1项，发表教研教改论文6篇，中文核心论文1篇。作为主要参与人员获广西高等教育自治区级教学成果奖二等奖3项、国家级一流本科课程1门、省级一流本科课程2门。
2015年入选广西高校青年教师教学业务能力提升计划第二期培养对象。
2018年入选广西高等学校千名中青年骨干教师培育计划第一期培养对象。
科研情况
主要从事新型多功能纳米光/电化学生物传感器的高效构筑和生物分析应用研究。主持国家级和省部级科研项目10余项，参与国家级科研项目10余项。以第一作者或通讯作者在国际权威学术期刊上发表学术论文60余篇，其中中科院大类一区论文10余篇，二区论文20余篇，被世界知名学者在包括Chem. Rev., Chem. Soc. Rev., Coordin. Chem. Rev., J. Am. Chem. Soc., Trac-Trend Anal. Chem., Anal. Chem., Chem. Commun., Biosens. Bioelectron.等国际顶级学术期刊正面评价和引用1500余次，其中单篇最高引用160余次，一篇论文入选ESI高被引论文。申请中国发明专利100余件，获授权60余件，转让50余件。受邀为Anal. Chem., ACS Appl. Mater. Interfaces, Chem. Commun., Biosens. Bioelectron., Carbon等20余个国际著名学术期刊评审相关稿件，在该领域的研究积累和工作基础得到国内外同行的认可与好评。作为主要参与人员获广西科学技术奖自然科学奖三等奖2项，获第八届广西青年学术年会论文二等奖2项，获第九届广西青年学术年会论文三等奖1项，获2020-2022年度广西分析测试协会优秀论文一等奖。
获奖情况
1、2021年获广西科学技术奖自然科学奖三等奖
2、2018年获广西科学技术奖自然科学奖三等奖
3、2022年获第九届广西青年学术年会论文三等奖
4、2019年获第八届广西青年学术年会论文二等奖2项
5、2022年获2020-2022年度广西分析测试协会优秀论文一等奖
6、2021年获广西高等教育自治区级教学成果奖二等奖
7、2019年获广西高等教育自治区级教学成果奖二等奖
8、2017年获广西高等教育自治区级教学成果奖二等奖
9、2022年获南宁师范大学“优秀园丁奖”
10、2021年获南宁师范大学“优秀共产党员”
11、2021年获2015-2020年南宁师范大学“优秀教师”
12、2021年获2018-2020年度南宁师范大学科研先进个人
13、2018年获广西师范学院第二届“教学新秀奖”
14、2017年获广西师范学院本科教学审核评估先进个人
15、2016年获广西师范学院高等教育校级教学成果奖一等奖
16、获广西师范学院2017年度科研工作先进个人
17、获广西师范学院2016年度科研工作先进个人
18、获广西师范学院2015年度科研工作先进个人
19、获2014-2015学年度广西师范学院教学工作优秀奖
20、获2013-2015年广西师范学院“优秀教师”
21、获广西师范学院2015年度“优秀班主任”
22、获广西师范学院2013年度“优秀班主任”
23、获2011-2012学年度广西师范学院教学工作优秀奖
主持承担科研项目
1、国家自然科学基金项目（22164014，35万元）：基于碳量子点荧光/磁共振双模态探针的高效构筑及其肿瘤靶向诊疗一体化应用研究。
2、国家自然科学基金项目（21864006，40万元）：基于靶向近红外碳量子点纳米生物传感器的构筑及其超高灵敏识别病毒核酸的应用基础研究。
3、国家自然科学基金项目（21403039，25万元）：基于生物热力学方法的芳杂环甾体抗肿瘤药物与端粒DNA相互作用机制研究。
4、中央引导地方科技发展资金项目（桂科ZY22096017，50万元）：多功能碳量子点纳米复合物的构筑及肝癌靶向诊疗应用基础研究。
5、第46批教育部留学回国人员科研启动基金项目（教外司留[2013]693号，3万元）：量子点FRET化学传感器用于有机磷农药残留可视化原位检测。
6、广西科学研究与技术开发计划项目（桂科能1598028-8，10万元）：饮用水中工业化学污染物靶向性高灵敏检测新技术与方法研究。
7、广西自然科学基金面上项目（2021GXNSFAA075015，10万元）：基于生物热力学方法的黑磷及其衍生物与蛋白质相互作用分子机制研究。
8、广西自然科学基金重点项目（2017GXNSFDA198034，40万元）：近红外碳量子点纳米生物传感器的构建及其对生物标志物的超高灵敏检测新方法研究。
9、广西自然科学基金面上项目（2015GXNSFAA139033，5万元）：基于芳基钌靶向抗肿瘤药物与端粒DNA相互作用机制研究。
10、广西自然科学基金青年基金项目（2013GXNSFBA019029，5万元）：基于海洋天然活性成分的甾体酰胺类抗肿瘤药物与端粒DNA相互作用机制研究。
11、污染物分析与资源化技术湖北省重点实验室开放基金（PA220202，2万元）：碳量子点荧光传感器的构筑及其有机磷农药残留可视化原位检测新方法研究。
12、广西高等教育本科教学改革工程项目一般A类（2015JGA284，2万元）：基于“翻转课堂”理念的高师化学教学改革与实践研究。
13、广西高校科研项目（2013YB138，3万元）：基于海洋天然活性成分的甾体酰胺类抗肿瘤药物与端粒DNA相互作用机制研究。
主要学术论文（* 通讯作者）
2023年
1. Qi Xiao*, Huajian Luo, Huishan Cao, Bo Li, Jiajia Liu, Yi Liu, Shan Huang*. Investigation on conformational variation and enzymatic activity of trypsin affected by Ti3C2 QDs via spectroscopic technique and molecular modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2023, 285, 121878.
2. Yali Wang, Shuai Liu, Dongyou Zhang, Qi Xiao*, Shan Huang*. Ultrasensitive electrochemical platform for p53 gene via molecular beacon-mediated circular strand displacement and terminal deoxynucleotidyl transferase-mediated signal amplification strategy. Analyst 2023. DOI: 10.1039/D2AN01676A
3. Qi Xiao*, Xincong Tu, Huishan Cao, Huajian Luo, Bo Li, Jiajia Liu, Yi Liu, Shan Huang*. Interaction thermodynamics investigation of bovine serum albumin with black phosphorus quantum dots via spectroscopic and molecular simulation techniques. Journal of Molecular Structure 2023, 1276, 134725.
4. Jiajia Liu, Bo Li, Lingxin Kong, Qi Xiao*, Shan Huang*. Surfactants-assisted morphological regulation of BiVO4 nanostructures for photocatalytic degradation of organic pollutants in wastewater. Journal of Physics and Chemistry of Solids 2023, 172, 111079.
5. Rukui Zhu, Yu Liang, Huajian Luo, Huishan Cao, Yi Liu, Shan Huang*, Qi Xiao*. Investigations of interaction mechanism and conformational variation of serum albumin affected by artemisinin and dihydroartemisinin. Journal of Molecular Recognition 2023, 36, e3000.
2022年
1. Gan Ning, Pingping Mu, Bo Li, Jiajia Liu, Qi Xiao*, Shang Huang*. Fluorine and nitrogen co-doped near-infrared carbon dots for fluorescence “on-off-on” determination of nitrite. Microchimica Acta 2022, 189, 230.
2. Gan Ning, Bo Li, Jiajia Liu, Qi Xiao*, Shang Huang*. Red‑emission carbon dots as fluorescent “on-off-on” probe for highly sensitive and selective detection of Cu2+ and glutathione. Analytical and Bioanalytical Chemistry 2022, 414, 2219−2233.
3. Shan Huang*, Jiandong Yao, Gan Ning, Bo Li, Pingping Mu, Qi Xiao*. Ultrasensitive ratiometric fluorescent probe for Hg(II) and trypsin activity based on carbon dots and metalloporphyrin via target recycling amplification strategy. Analyst 2022, 147, 1457−1466.
4. Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao*, Shan Huang*. A label-free and ultrasensitive electrochemical biosensor for oral cancer overexpressed 1 gene via exonuclease III-assisted target recycling and dual enzymes-assisted signal amplification strategies. Analyst 2022, 147, 2412−2424.
5. Dongyou Zhang, Yali Wang, Xiaoyu Jin, Qi Xiao*, Shan Huang*. Ultrasensitive electrochemical biosensor for HPV16 oncogene based on Y-shaped DNA catalytic hairpin assembly and template-free DNA extension reaction. Electroanalysis 2022, 34, 1001−1011.
2021年
1. Huajian Luo, Bo Li, Jiajia Liu, Yi Liu, Qi Xiao*, Shang Huang*. Investigation on conformational variation and fibrillation of human serum albumin affected by molybdenum disulfide quantum dots. International Journal of Biological Macromolecules 2021, 190, 999−1006.
2. Shan Huang, Jiandong Yao, Bo Li, Gan Ning, Qi Xiao*. Integrating target-responsive CD-CdTe QD-based ratiometric fluorescence hydrogel with smartphone for visual and on-site determination of dichlorvos. Microchimica Acta 2021, 188, 318.
3. Huajian Luo, Haimei Li, Yi Liu, Liyun Yang, Qi Xiao*, Shan Huang*. Investigation on conformational variation and activity of trypsin affected by black phosphorus quantum dots via multi-spectroscopy and molecular modeling. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2021, 256, 119746.
4. Shan Huang*, Xiaoyu Jin, Dongyou Zhang, Yali Wang, Dan Wang, Qi Xiao*, Wenxi Zhang. Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of p53 gene based on nicking endonuclease-assisted target recycling and rolling circle amplification. Microchemical Journal 2021, 168, 106461.
5. Huajian Luo, Yu Liang, Huiying Zhang, Yi Liu, Qi Xiao*, Shan Huang*. Comparison on binding interactions of quercetin and its metal complexes with calf thymus DNA by spectroscopic techniques and viscosity measurement. Journal of Molecular Recognition 2021, 34, e2933.
6. Shan Huang, Huajian Luo, Wei Su, Qi Xiao*, Jiangning Xie*. Comparative study of binding interactions between three organometallic rhodium(III) complexes with curcuminoid ligands and human serum albumin. Journal of Molecular Recognition 2021, 34, e2876.
7. 黄珊, 姚建东, 宁淦, 肖琦*, 刘义. 石墨烯量子点荧光探针对碱性磷酸酶活性的高效检测. 高等学校化学学报 2021, 42, 2412−2421.
8. 罗华健, 李海梅, 肖琦, 黄珊*, 刘义*. 三种不同元素掺杂的碳点与DNA相互作用及其机制研究. 中国科学：化学 2021, 51, 74−84.
2020年
1. Shan Huang, Haimei Li, Yi Liu, Liyun Yang, Dan Wang, Qi Xiao*. Investigations of conformational structure and enzymatic activity of trypsin after its binding interaction with graphene oxide. Journal of Hazardous Materials 2020, 392, 122285.
2. Shan Huang, Haimei Li, Huajian Luo, Liyun Yang, Zhiqiang Zhou, Qi Xiao*, Yi Liu*. Conformational structure variation of human serum albumin after binding interaction with black phosphorus quantum dots. International Journal of Biological Macromolecules 2020, 146, 405−414.
3. Shan Huang, Jiandong Yao, Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*. A ratiometric fluorescent assay for evaluation of alkaline phosphatase activity based on ionic liquid-functionalized carbon dots. Microchimica Acta 2020, 187, 271.
4. Xu Chu, Gan Ning, Zhiqiang Zhou, Yi Liu, Qi Xiao*, Shan Huang*. Bright Mn-doped carbon dots for the determination of permanganate and L-ascorbic acid by a fluorescence on-off-on strategy. Microchimica Acta 2020, 187, 659.
5. Qi Xiao, Jiandan Liang, Huajian Luo, Haimei Li, Jing Yang, Shan Huang*. Investigations of conformational structures and activities of trypsin and pepsin affected by food colourant allura red. Journal of Molecular Liquids 2020, 319, 114359.
6. Jiawen Li, Xiaoyu Jin, Mengmeng Feng, Shan Huang*, Jinrong Feng*. Ultrasensitive and highly selective electrochemical biosensor for HIV gene detection based on amino-reduced graphene oxide and β-cyclodextrin modified glassy carbon electrode. International Journal of Electrochemical Science 2020, 15, 2727−2738.
7. Haimei Li, Huajian Luo, Qi Xiao, Liyun Yang, Shan Huang*, Yi Liu*. Investigations of interactions and mechanisms of chiral graphene quantum dots with DNA. Acta Chimica Sinica 2020, 78, 577−586.
8. Shan Huang, Huajian Luo, Yi Liu, Wei Su, Qi Xiao*. Comparable investigation of binding interactions between three arene ruthenium(II) thiosemicarbazone complexes and calf thymus DNA. Polyhedron 2020, 192, 114864.
2019年
1. Qi Xiao*, Jiawen Li, Xiaoyu Jin, Yi Liu, Shan Huang*. Ultrasensitive electrochemical microRNA-21 biosensor coupling with carboxylate-reduced graphene oxide-based signal-enhancing and duplex-specific nuclease-assisted target recycling. Sensors and Actuators B: Chemical 2019, 297, 126740.
2. Shan Huang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*, Yue Zhang*. One-step facile synthesis of nitrogen-doped carbon dots: A ratiometric fluorescent probe for evaluation of acetylcholinesterase activity and detection of organophosphorus pesticides in tap water and food. Journal of Agricultural and Food Chemistry 2019, 67, 11244−11255.
3. Qi Xiao, Jinrong Feng, Mengmeng Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. A ratiometric electrochemical aptasensor for ultrasensitive determination of adenosine triphosphate via triple-helix molecular switch. Microchimica Acta 2019, 186, 478.
4. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Qi Xiao*. Nitrogen, phosphorus and sulfur tri-doped carbon dots are specific and sensitive fluorescent probes for determination of chromium(VI) in waters samples and in living cells. Microchimica Acta 2019, 186, 851.
5. Shan Huang, Erli Yang, Jiandong Yao, Xu Chu, Yi Liu, Yue Zhang, Qi Xiao*. Nitrogen, cobalt co-doped magnetic carbon dots as a ratiometric fluorescence universal platform for cholesterol and uric acid in human blood serum. ACS Omega 2019, 4, 9333−9342.
6. Erli Yang, Jiandong Yao, Lumin Wang, Yi Liu, Qi Xiao, Shan Huang*. InP/ZnS quantum dot-based fluorescent probe for directly sensitive and selective detection of horseradish peroxidase. Methods and Applications in Fluorescence 2019, 7, 035008.
7. Qi Xiao, Jinrong Feng, Jiawen Li, Yi Liu, Dan Wang, Shan Huang*. Ratiometric electrochemical biosensor for ultrasensitive and highly selective detection of K-ras gene via exonuclease III-assisted target recycling and rolling circle amplification strategies. Analytical Methods 2019, 11, 4146−4156.
8. Shan Huang, Haimei Li, Yi Liu, Yu Liang, Wei Su, Qi Xiao*. Comparable investigation of in vitro interactions between three ruthenium(II) arene complexes with curcumin analogs and ctDNA. Polyhedron 2019, 167, 51−61.
2018年
1. Shan Huang, Erli Yang, Yi Liu, Jiandong Yao, Wei Su, Qi Xiao*. Low-temperature rapid synthesis of nitrogen and phosphorus dual-doped carbon dots for multicolor cellular imaging and hemoglobin probing in human blood. Sensors and Actuators B: Chemical 2018, 265, 326−334.
2. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Carbon dots doped with nitrogen and boron as ultrasensitive fluorescent probes for determination of α-glucosidase activity and its inhibitors in water samples and living cells. Microchimica Acta 2018, 185, 394.
3. Shan Huang, Mengmeng Feng, Jiawen Li, Yi Liu, Qi Xiao*. Voltammetric determination of attomolar levels of a sequence derived from the genom of hepatitis B virus by using molecular beacon mediated circular strand displacement and rolling circle amplification. Microchimica Acta 2018, 185, 206.
4. Shan Huang, Erli Yang, Jiandong Yao, Yi Liu, Qi Xiao*. Red emission nitrogen, boron, sulfur co-doped carbon dots for “on-off-on” fluorescent mode detection of Ag+ ions and L-cysteine in complex biological fluids and living cells. Analytica Chimica Acta 2018, 1035, 192−202.
5. Qi Xiao, Jinrong Feng, Jiawen Li, Mengmeng Feng, Shan Huang*. A label-free and ultrasensitive electrochemical aptasensor for lead(II) using a N,P dual-doped carbon dot-chitosan composite as a signal-enhancing platform and thionine as a signaling molecule. Analyst 2018, 143, 4764−4773.
6. Shan Huang, Yu Liang, Jianguo Cui*, Jiangning Xie, Yi Liu, Baoqing Hu, Qi Xiao*. Comparative investigation of binding interactions with three steroidal derivatives of d(GGGT)4 G-quadruplex aptamer. Steroids 2018, 132, 46−55.
7. Qi Xiao, Mengmeng Feng, Yi Liu, Shuangyan Lu, Yingzi He, Shan Huang*. The graphene/polypyrrole/chitosan-modified glassy carbon electrode for electrochemical nitrite detection. Ionics 2018, 24, 845−859.
8. Shan Huang, Erli Yang, Lumin Wang, Yi Liu, Jiangning Xie, Baoqing Hu, Qi Xiao*. Carbon dots-based frequency-doubling scattering probes for the ultrasensitive and highly selective determination of hemoglobin. Analytical Methods 2018, 10, 891−899.
9. Qi Xiao, Yu Liang, Yi Liu, Shuangyan Lu, Shan Huang*. Comparison of molecular interactions of Ag2Te and CdTe quantum dots with human serum albumin by spectroscopic approaches. Luminescence 2018, 33, 181−189.
2017年
1. Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Label-free and ratiometric fluorescent nanosensor based on amino-functionalized graphene quantum dots coupling catalytic G-quadruplex/hemin DNAzyme for ultrasensitive recognition of human telomere DNA. Sensors and Actuators B: Chemical 2017, 245, 648−655.
2. Qi Xiao, Yu Liang, Fawei Zhu, Shuangyan Lu, Shan Huang*. Microwave-assisted one-pot synthesis of highly luminescent N-doped carbon dots for cellular imaging and multi-ion probing. Microchimica Acta 2017, 184, 2429−2438.
3. Shan Huang, Jiangning Xie, Jianguo Cui*, Liang Liu, Yu Liang, Yi Liu, Qi Xiao*. Comparative investigation of binding interactions between three steroidal compounds and human serum albumin: Multispectroscopic and molecular modeling techniques. Steroids 2017, 128, 136−146.
4. Shan Huang, Jiangning Xie, Wei Su, Yi Liu, Xiaohui Wang, Baoqing Hu, Qi Xiao*. Comparative investigation of interactions between two ruthenium(II) arene PTA type complexes with curcuminoid ligands and human serum albumin. Journal of Organometallic Chemistry 2017, 853, 81−92.
5. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shuyu Zhou, Jiarong Sheng, Shan Huang*. An electrochemical chiral sensor based on amino-functionalized graphene quantum dots/β-cyclodextrin modified glassy carbon electrode for enantioselective detection of tryptophan isomers. Journal of the Iranian Chemical Society 2017, 14, 1957−1970.
2016年
1. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Lixia Zhang, Wei Su, Qi Xiao*. An electrochemical biosensor based on single-stranded DNA modified gold electrode for acrylamide determination. Sensors and Actuators B: Chemical 2016, 224, 22−30.
2. Shan Huang, Lumin Wang, Chusheng Huang, Wei Su, Qi Xiao*. Amino-functionalized graphene quantum dots based ratiometric fluorescent nanosensor for ultrasensitive and highly selective recognition of horseradish peroxidase. Sensors and Actuators B: Chemical 2016, 234, 255−263.
3. Shan Huang, Lumin Wang, Chusheng Huang, Baoqing Hu, Wei Su, Qi Xiao*. Graphene quantum dot coupled with gold nanoparticle based “off-on” fluorescent probe for sensitive and selective detection of L-cysteine. Microchimica Acta 2016, 183, 1855−1864.
4. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Jianguo Cui, Wei Su, Qi Xiao*. Systematical investigation of in vitro interaction of InP/ZnS quantum dots with human serum albumin by multispectroscopic approach. Colloids and Surfaces B: Biointerfaces 2016, 148, 165−172.
5. Shan Huang, Shushu Peng, Wei Su, Zhaofeng Tang, Jianguo Cui, Chusheng Huang, Qi Xiao*. In vitro interaction investigation between three Ru(II) arene complexes and human serum albumin: Structural influences. RSC Advances 2016, 6, 47043−47054.
6. Shan Huang, Hangna Qiu, Jiangning Xie, Chusheng Huang, Wei Su, Baoqing Hu, Qi Xiao*. Systematical investigation of in vitro molecular interaction between fluorescent carbon dots and human serum albumin. RSC Advances 2016, 6, 44531−44542.
7. Qi Xiao, Shuangyan Lu, Chusheng Huang, Wei Su, Shan Huang*. Novel N-doped carbon dots/β-cyclodextrin nanocomposites for enantioselective recognition of tryptophan enantiomers. Sensors 2016, 16, 1874.
8. Shan Huang, Shushu Peng, Fawei Zhu, Xiaolin Lei, Qi Xiao*, Wei Su, Yi Liu, Chusheng Huang, Lixia Zhang. Multispectroscopic investigation of the interaction between two ruthenium(II) arene complexes of curcumin analogs and human serum albumin. Biological Trace Element Research 2016, 169, 189−203.
9. Shan Huang, Yu Liang, Chusheng Huang, Wei Su, Xiaolin Lei, Yi Liu, Qi Xiao*. Systematical investigation of binding interaction between novel ruthenium(II) arene complex with curcumin analogs and ctDNA. Luminescence 2016, 31, 1384−1394.
2015年
1. Shan Huang, Hangna Qiu, Shuangyan Lu, Fawei Zhu, Qi Xiao*. Study on the molecular interaction of graphene quantum dots with human serum albumin: Combined spectroscopic and electrochemical approaches. Journal of Hazardous Materials 2015, 285, 18−26.
2. Shan Huang, Lumin Wang, Chusheng Huang, Jiangning Xie, Wei Su, Jiarong Sheng, Qi Xiao*. A carbon dots based fluorescent probe for selective and sensitive detection of hemoglobin. Sensors and Actuators B: Chemical 2015, 221, 1215−1222.
3. Shan Huang, Hangna Qiu, Fawei Zhu, Shuangyan Lu, Qi Xiao*. Graphene quantum dots as on-off-on fluorescent probes for chromium(VI) and ascorbic acid. Microchimica Acta 2015, 182, 1723−1731.
4. Shan Huang, Shuangyan Lu, Chusheng Huang, Jiarong Sheng, Wei Su, Lixia Zhang, Qi Xiao*. Sensitive and selective stripping voltammetric determination of copper(II) using a glassy carbon electrode modified with amino-reduced graphene oxide and β-cyclodextrin. Microchimica Acta 2015, 182, 2529−2539.
5. Shan Huang, Hangna Qiu, Yi Liu, Chusheng Huang, Jiarong Sheng, Wei Su, Qi Xiao*. Molecular interaction investigation between three CdTe:Zn2+ quantum dots and human serum albumin: A comparative study. Colloids and Surfaces B: Biointerfaces 2015, 136, 955−962.
6. Shan Huang, Lumin Wang, Fawei Zhu, Wei Su, Jiarong Sheng, Chusheng Huang, Qi Xiao*. A ratiometric nanosensor based on fluorescent carbon dots for label-free and highly selective recognition of DNA. RSC Advances 2015, 5, 44587−44597.
7. Shan Huang, Fawei Zhu, Qi Xiao*, Yu Liang, Quan Zhou, Wei Su*. Thermodynamic investigation of the interaction between the [(η6-p-cymene)Ru(benzaldehyde-N4-phenylthiosemicarbazone)Cl]Cl anticancer drug and ctDNA: multispectroscopic and electrochemical studies. RSC Advances 2015, 5, 42889−42902.
8. Shan Huang, Fawei Zhu, Quanquan Qian, Qi Xiao*, Wei Su*. Thermodynamic investigation of interaction between [(η6-p-cymene)RuII(acetone-N4-phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin: Spectroscopic and electrochemical studies. Biological Trace Element Research 2015, 164, 150−161.
2014年
1. Shan Huang*, Fawei Zhu, Hangna Qiu, Qi Xiao*, Quan Zhou, Wei Su*, Baoqing Hu. A sensitive quantum dots-based “OFF-ON” fluorescent sensor for Ruthenium anticancer drugs and ctDNA. Colloids and Surfaces B: Biointerfaces 2014, 117, 240−247.
2. Shan Huang, Fawei Zhu, Qi Xiao*, Wei Su, Jiarong Sheng, Chusheng Huang, Baoqing Hu. A CdTe/CdS/ZnS core/shell/shell QDs-based “OFF-ON” fluorescent biosensor for sensitive and specific determination of L-ascorbic acid. RSC Advances 2014, 4, 46751−46761.
3. Shan Huang, Fawei Zhu, Qi Xiao*, Quan Zhou, Wei Su*, Hangna Qiu, Baoqing Hu, Jiarong Sheng, Chusheng Huang. Combined spectroscopy and cyclic voltammetry investigates the interaction between [(η6-p-cymene)Ru(benzaldehyde-N(4)-phenylthiosemicarbazone)Cl]Cl anticancer drug and human serum albumin. RSC Advances 2014, 4, 36286−36300.
2013年
1. Shan Huang, Guozhu Chen, Mohamed Chaker, Tsuneyuki Ozaki, Peter Tijssen, Dongling Ma*. Fluorescent-magnetic multifunctional nanoparticles for imaging and drug delivery. Reviews in Nanoscience and Nanotechnology 2013, 2, 346−364.
2. Shan Huang, Qi Xiao*, Wei Su, Peiyuan Li, Jianqiang Ma, Zhike He. Simple and sensitive determination of papain by resonance light-scattering with CdSe quantum dots. Colloids and Surfaces B: Biointerfaces 2013, 102, 146−151.
3. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Jianqiang Ma, Fenping Luo, Jing Chen, Yi Liu*. Systematically investigations of conformation and thermodynamics of HSA adsorbed to different sizes of CdTe quantum dots. Colloids and Surfaces B: Biointerfaces 2013, 102, 76−82.
4. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Yi Liu*. Evaluate the potential toxicity of quantum dots on bacterial metabolism by microcalorimetry. Thermochimica Acta 2013, 552, 98−105.
5. Qi Xiao, Hangna Qiu, Shan Huang*, Chusheng Huang, Wei Su, Baoqing Hu, Yi Liu*. Systematic investigation of interactions between papain and MPA-capped CdTe quantum dots. Molecular Biology Reports 2013, 40, 5781−5789.
6. Shan Huang, Hangna Qiu, Qi Xiao*, Chusheng Huang, Wei Su, Baoqing Hu. A simple QD-FRET bioprobe for sensitive and specific detection of hepatitis B virus DNA. Journal of Fluorescence 2013, 23, 1089−1098.
7. Shan Huang, Jianqiang Ma, Qi Xiao*, Mingyue Dong, Xuehua Li, Qiuling Luo. Direct determinaiton of isocarbophos by using oil soluble CdSe quantum dots as fluorescent probe. Spectroscopy and Spectral Analysis 2013, 33, 2853−2857.
2012年
1. Qi Xiao, Shan Huang*, Wei Su, WH Chan*, Yi Liu*. Facile synthesis and characterization of highly fluorescent and biocompatible N-acetyl-L-cysteine capped CdTe/CdS/ZnS core/shell/shell quantum dots in aqueous phase. Nanotechnology 2012, 23, 495717.
2. Qi Xiao, Shan Huang*, Jianqiang Ma, Wei Su, Peiyuan Li, Jianguo Cui, Yi Liu*. Systematically investigation of interactions between BSA and different charge-capped CdSe/ZnS quantum dots. Journal of Photochemistry and Photobiology A: Chemistry 2012, 249, 53−60.
3. Qi Xiao, Shan Huang*, Wei Su, Peiyuan Li, Zuocui Liang, Jianzhen Ou, Jianqiang Ma, Yi Liu*. Evaluate the potential environmental toxicity of quantum dots on ciliated protozoa by microcalorimetry. Thermochimica Acta 2012, 547, 62−69.
4. Qi Xiao, Ting Qiu, Shan Huang, Yi Liu*, Zhike He*. Preparation and biological effect of nucleotide capped CdSe/ZnS quantum dots on Tetrahymena Thermophila. Biological Trace Element Research 2012, 147, 346−353.
2011年及以前
1. Shan Huang, Qi Xiao, Zhike He*, Yi Liu, Philip Tinnefeld, Xiongrui Su, Xiaoniu Peng. A high sensitive and specific QDs FRET bioprobe for MNase. Chemical Communications 2008, 45, 5990−5992.
2. Shan Huang, Qi Xiao, Ran Li, Hongliang Guan, Jiang Liu, Xiaorong Liu, Zhike He*, Yi Liu. A simple and sensitive method for L-cysteine detection based on the fluorescence intensity increment of quantum dots. Analytica Chimica Acta 2009, 645, 73−78.
3. Qi Xiao, Bo Zhou, Shan Huang, Fangfang Tian, Hongliang Guan, Yushu Ge, Xiaorong Liu, Zhike He, Yi Liu*. Direct observation of the binding process between protein and quantum dots by in-situ surface plasmon resonance measurements. Nanotechnology 2009, 20, 325101.
4. Yong Lei, Qi Xiao, Shan Huang, Wansu Xu, Zhe Zhang, Zhike He, Yi Liu*, Fengjiao Deng*. Impact of CdSe/ZnS quantum dots on the development of zebrafish embryos. Journal of Nanoparticle Research 2011, 13, 6895−6906.
5. Qi Xiao, Shan Huang, Yushu Ge, Zhike He*, Yi Liu, Jiangong Liang. A novel fluorescent silver ion biosensor based on nucleic acid molecular "light switch". Journal of Fluorescence 2010, 20, 541−549.
6. Qi Xiao, Shan Huang, Yi Liu*, Fangfang Tian, Juncheng Zhu. Thermodynamics, Conformation and active sites of the binding of Zn-Nd hetero-bimetallic schiff base to bovine serum albumin. Journal of Fluorescence 2009, 19, 317−326.
7. Qi Xiao, Shan Huang, Zude Qi, Bo Zhou, Zhike He, Yi Liu*. Conformation, thermodynamics and stoichiometry of HSA adsorbed to colloidal CdSe/ZnS quantum dots. BBA-Proteins and Proteomics 2008, 1784, 1020−1027.
8. Shan Huang, Qi Xiao, Zhike He*, Yi Liu. Resonance light scattering method for the determinaiton of lysozyme using CdSe quantum dots as probe. Chemical Journal of Chinese Universities-Chinese 2009, 30, 1951−1955.
9. Shan Huang, Zhike He*. Quantum dots-ssDNA-fluorescent dye conjugates as bioprobes for specific and sensitive detection of DNase. Luminescence 2008, 23, 73.
主要授权发明专利
1. 黄珊，肖琦，姚建东。基于目标响应水凝胶与手机套件检测有机磷农药的方法。专利号：ZL202010627304.6
2. 黄珊，肖琦，姚建东。基于碳点与碲化镉量子点作为荧光探针检测有机磷农药的方法。专利号：ZL202010628529.3
3. 黄珊，肖琦，杨二利，褚旭。钴掺杂磁性碳量子点的制备方法及检测尿酸的方法。专利号：ZL201910213630.X
4. 黄珊，肖琦，杨二利，褚旭。钴掺杂磁性碳量子点的制备方法及检测胆固醇的方法。专利号：ZL201910214457.5
5. 黄珊，肖琦，姚建东。基于酶与氧化石墨烯适配体传感器检测凝血酶的方法。专利号：ZL201710935015.0
6. 黄珊，肖琦，杨二利，刘义。激发发射波长依赖浓度的水溶性氮磷共掺杂碳量子点的制备方法。专利号：ZL201710618097.6
7. 黄珊，肖琦，杨二利，刘义。利用氮磷掺杂碳量子点探针检测六价铬的方法。专利号：ZL201710617996.4
8. 黄珊，肖琦，杨二利，刘义。利用水溶性橙色荧光碳量子点探针检测血红蛋白的方法。专利号：ZL201710617999.8
9. 黄珊，肖琦，杨二利，刘义。利用氮磷掺杂碳量子点探针检测芳基钌的方法。专利号：ZL201710619620.7
10. 黄珊，肖琦，杨二利，刘义。利用氮磷掺杂碳量子点探针检测血红蛋白的方法。专利号：ZL201710619645.7
11. 黄珊，肖琦，杨二利，刘义。水溶性氮硫磷共掺杂碳量子点的制备方法。专利号：ZL201710619125.6
12. 黄珊，肖琦，杨二利，刘义。水溶性氮磷硼共掺杂碳量子点的制备方法。专利号：ZL201710619653.1
13. 黄珊，肖琦，卢双燕。检测溶液中酪氨酸浓度的方法。专利号：ZL201610619910.7
14. 黄珊，肖琦，卢双燕。检测溶液中天冬酰胺浓度的方法。专利号：ZL201610619894.1
15. 黄珊，肖琦，卢双燕。检测溶液中天冬氨酸浓度的方法。专利号：ZL201610614973.3
16. 黄珊，肖琦，卢双燕。检测溶液中D型色氨酸浓度的方法。专利号：ZL201610614989.4
17. 黄珊，肖琦，卢双燕。检测溶液中L型色氨酸浓度的方法。专利号：ZL201610614975.2
18. 黄珊，肖琦，王鲁敏，谢江宁。一种利用荧光碳点探针检测高锰酸钾的方法。专利号：ZL201510034187.1
19. 黄珊，肖琦，丘杭娜，王鲁敏，盛家荣，苏炜，朱发伟。利用石墨烯量子点探针检测三价铬离子的方法。专利号：ZL201410530762.2
