刘志平
学历/职称：博士/副教授、硕士研究生导师
招生专业：有机化学、材料与化工和学科教学（化学）
联系方式：liuzhiping828@126.com
教育与工作经历：
1. 2013.12 广西大学化学工艺专业，工学博士；
2. 2005.7-至今 南宁师范大学化学与材料学院教师
研究方向：
1. 天然活性物质的筛选与开发；
2. 活性药物/农药分子的设计与合成；
3. 中学化学教学方法与试题研究；
研究课题：
1. 校企研发项目：硫（硒）氰酸酯农用抑菌剂的研究开发（2024450001000705），主持，在研；
2. 校企研发项目：防控水稻抗性螟虫亚胺类新药的创制（2023450001000483），主持，已结题；
3. 广西自然科学基金2020GXNSFAA159096，三元张力杂环可调控双模式开环反应构建杂环体系的应用，主持, 已结题；
4. 广西自然科学基金2014GXNSFBA118033，点击合成三氮唑二氢黄酮肟类化合物及抗肿瘤活性研究，主持，已结题；
5. 国家自然科学基金项目21762008，“基于雌激素受体下调的甾体化合物分子设计、合成及抗乳腺癌机制研究”，参加，已结题。
6. 国家自然科学基金21462009，具有特殊甾核结构甾体杂环化合物的设计、合成及生物活性评估，参加，已结题；
7. 广西自然科学基金2018GXNSFBA138037，金属-有机双功能催化剂的功能导向合成与不对称催化应用，参加，已结题；
8. 广西创新驱动专项桂AA18242027，环保控释农药的制备技术研究及产业化，参加，已结题；
9. 2023 年广西高等教育本科教学改革工程项目“‘三阶式’培养高师师范生微课题研究能力的探索与实践”（2023JGA240）；主持，已结题
10. 2022年广西高等教育本科教学改革工程项目“师范专业认证背景下践行 OBE 理念的高师生实践教育研究”（2022JGA248）参加，已结题
11. 2025 年广西学位与研究生教育改革课题“基于“素养导向”的专业学位研究生创新能力及职业发展路径研究”（JGY2025280）；主持，在研
主要学术论文：
2026年
1. Zhiping Liu, Chunrui Cai, Wenhao Tian, Qiang Hu, Taichen Yang, Yanmin Huang*, Weiguo Li, Jianguo Cui*, Excellent inhibitory activity of aromatic selenocyanates against phytopathogenic bacterium and structure-activity relationship, Pest Management Science, 2026, 82, 3942-3954
2. Xiyan Tang, Jie Pang, Yanmin Huang, Jianguo Cui, Chunfang Gan, Zhiping Liu*, Evaluation of the antibacterial activity of diverse coumarin [3,4]-fused tetrahydroheterocycles, Bioorganic & Medicinal Chemistry Letters, 2026, 132, 130468
3. Zhiping Liu, Yinze Liang, Junyan Li, Weiguo Li, Yanmin Huang*, Taichen Yang, Qiang Hu, Jianguo Cui*, Structural modification of fipronil-5-amino and insecticidal activity evaluation of its derivatives against resistant Chilo suppressalis, Pest Management Science, 2026, 82, 3842-3852
4. Zhi-Ping Liu*, Mai-Xia Liu, Chun-Rui Cai, Chun-Fang Gan, Jian-Guo Cui, Yan-Min Huang*, Synthesis and antibacterial activity of naringenin derivatives containing selenocyanate moiety, Journal of Asian Natural Products Research, 2026, 28
5. Zhipin Liu, Jiansheng Li, Yanmin Huang*, Weiguo Li, Chunrui Cai, Qiang Hu, Yanlin Chen, Jianguo Cui*. Lufenuron dual-carrier nanoformulation: Controlled release and systemic translocation via β-cyclodextrin octadecanoate and urea-formaldehyde resin, Langmuir, 2026,42，
6. Xiyan Tang, Lijie Che, Yanmin Huang, Jianguo Cui, Zhiping Liu*, Synthesis and structure-activity relationships of chlordimeform imine analogues against Chilo suppressalis. Synthetic Communications, 2026, 56
2025年
1. Zhiping Liu*; Lijie Che; Jie Pang; Juanan Xiao; Xiyan Tang; Chunfang Gan; Jianguo Cui; Yanmin Huang*, Cu(OTf)2 Catalyzed the Reaction of Donor-Acceptor Cyclopropanes With Salicylaldehyde Phenylhydrazones: Synthesis Polycyclic Tetrahydropyridazines, Journal of Heterocyclic Chemistry, 2025, 62: 402-413
2. Zhiping Liu*, Lijie Che, Yunlong Ban, Maixia Liu, Xiyan Tang, Yanmin Huang, Jianguo Cui, Chunfang Gan*, Synthesis and antiproliferative evaluation of novel chrysin selenocyanates. Synthetic Communications, 2025, 55(3): 259-269
3. Maixia Liu, Lijie Che, Xiyan Tang, Chunfang Gan, Yanmin Huang, Zhiping Liu*, Synthesis and antitumor activity of selenocyanate derivatives based on 2-amino-5-(4-chlorophenyl) furan/thiophene scaffolds, Synthetic Communications, 2025, 55(16): 1257–1264
4. Lan Zheng, Yumin Yang, Zhiping Liu*, Wei Wang, Wenjie Liang, Hailian Jiang, Liu Yang, Chenxiang Lin*., Wei Su, Junan Xiao*. Palladium-Catalyzed Strain-Enabled [2π+2σ] Cycloadditions of Vinyl Bicyclo[1.1.0]butanes with Methyleneindolinones. Organic Letters, 2025, 27(1): 229-234.
5. Zhiping Liu*, Lijie Che, Jie Pang, Xiyan Tang, Chunfang Gan, Jianguo Cui, Yanmin Huang*. Design, Synthesis, and antiproliferative activity of new selenocyanate-containing selenophenol amide derivatives. Journal of Heterocyclic Chemistry, 2025, 62:720–729
6. Zhiping Liu*, Lijie Che, Maixia Liu, Xiyan Tang, Chunfang Gan, Haifeng Chen, Jianguo Cui, Yanmin Huang*.. Synthesis and antiproliferative activities of amidethiophene selenocyanates. Journal of Sulfur Chemistry, 2025, 46:1172-1190
7. Zhiping Liu, Junan Li, Yinze Liang, Yanmin Huang*., Tao Gan, Chunrui Cai, Jianguo Cui*. . Design, Synthesis, and insecticidal activity of novel fipronil derivatives incorporating a sulfide unit. Organic Preparations and Procedures International, 2025,57,519-531.
8. Yanmin Huang, Jiansheng Li, Zhipin Liu, Qiang Hu, Qiucui Yao*, Chunfang Gan, Qipeng Xiong, Jianguo Cui*.. Dual-coated emamectin benzoate nano-formulation with enhanced systemic translocation and insecticidal activity based on lignin/urea-formaldehyde. International Journal of Biological Macromolecules, 2025,331: 148498
9. Yanmin Huang, Yang Cheng, Wenhao Tian, Zhiping Liu, Chunfang Gan, Haifeng Chen*., Tao Gan, Chunrui Cai, Jianguo Cui*.. Synthesis and preliminary evaluation of estradiol diselenocyanate derivatives as potential antitumor agents, Journal of Steroid Biochemistry and Molecular Biology, 2025, 252:106771
2024年
1. Zhiping Liu*; Jie Pang; Lijie Che; Chunfang Gan; Jianguo Cui; Yanmin Huang*, GaCl3‐Catalyzed [3+2]-Cycloaddition/Esterification Cascade of Donor–Acceptor Cyclopropanes With Salicylaldehydes for the Synthesis of Tetrahydro‐4H‐Furo[3,2‐c]Chromen‐4‐Ones, Journal of Heterocyclic Chemistry, 2024, 61: 1953-1965
2. Chunfang Gan, Ying Li, Hualong Chen, Jiawei Yao, Yunqiong Gu, Bin Su, Zhiwei Zhong, Jianguo Cui, Yanmin Huang, Zhiping Liu*. Synthesis and antiproliferative activity of 7-substituted amide estradiol derivatives. Medicinal Chemistry Research, 2024, 33(10): 1954-1973 https://doi.org/10.1007/s00044-024-03301-4
3. Jinshao Liang, Lihong Ruan, Xurong Shi, Yinzhi Chen, Chuhuang Song, Jun'an Xiao, Zhiping Liu*, Mechanochemistry Enabled Friedel-Crafts Alkylation Reactions of Donor-Acceptor Cyclopropanes with 2-Indolymethanols, Chinese Journal of Organic Chemistry, 2024, 44(11): 3437-3445 https://doi.org/10.6023/cjoc202404006
4. Zhiping Liu*; Jie Pang; Lijie Che; Liping Pang; Chunfang Gan; Jianguo Cui; Yanmin Huang*, Sc(OTf)3‐catalyzed tandem (3+3)‐annulation/lactonization of cyclopropanes with salicylaldehyde nitrones to access polycyclic 1,2‐oxazines. Journal of Heterocyclic Chemistry, 2024, 61:474-482
5. Yanmin Huang; Yang Cheng; Meizhen Wei; Zining Peng; Wenhao Tian; Zhiping Liu*; Junyan Li; Jianguo Cui*, Synthesis, antitumor activity evaluation of 2-selenocyano-3- selenocyanoalkyloxyestradiols with a bisselenocyanate structure. Bioorganic Chemistry, 2024, 144: 107149-107162.
6. Tao Gan, Yang Cheng, Wenhao Tian, Zhiping Liu, Chunfang Gan, Yanmin Huang*, Chunrui Cai, Jianguo Cui*, Synthesis of novel estradiol bisselenocyanate with unique 2-selenocyano-17-selenocyanoesteryl structure and evaluation of antitumor activity. Molecular Diversity, 2024, 12: 1-15
2023年前
1. Yanmin Huang; Zining Peng; Chang Liu; Chunling Pang; Sijing Chen; Chunfang Gan; Zhiping Liu*; jianguo Cui*, Synthesis and antiproliferative activity evaluation of B-norcholesterol-6-amide compounds, Medicinal Chemistry, 2023, 19: 813-822
2. Yanmin Huang, Wenhao Tian, Zining Peng, Yang Cheng, Meizhen Wei, Zhiping Liu, Liping Pang, Jianguo Cui*, Discovery and biological evaluation of pregnenolone selenocyanoamides with potential anticancer and antimicrobial activities. Journal of Steroid Biochemistry and Molecular Biology 2023, 234: 106388
3. Zhu Zhiling; Liu Zhiping; Cui Jianguo; Huang Yanmin; Chem Hualong; Wu Yulan; Huang Xiaotong; Gan Chunfang*, Apoptosis inducing properties of 3-biotinylate-6-benzimidazole B-nor-cholesterol analogues, Steroids, 2021, 169(10): 108822-108828.
4. Liu Zhiping*; Li Jinlian; Cheng Xiuliang; Cui Jianguo; Huang Yanmin; Gan Chunfang; Su Wei; Xiao junan*, Visible-Light-Induced Ring-Opening of Hydrogenolysis Spirocyclopropyl Oxindoles Through Photoredox Catalysis, Eur. J. Org. Chem., 2019, 2019(4): 4085-4088.
5. Liu Zhiping; Wei Wanxing*; Gan Chunfang; Huang Yanmin; Liu Sheng; Zhou Min; Cui Jianguo. Synthesis and Cytotoxicity of N-Benzylidene Hesperitin Hydrazones and Analogues. Chinese Journal of Organic Chemistry, 2013, 33(9): 1988-1993.
6. Liu Zhiping; Wei Wanxing*; Gan Chunfang; Huang Yanmin; Liu Sheng; Cui Jianguo. Synthesis and Cytotoxicity of E-Hesperetin Oximes against SGC-7901. Chinese Journal of Organic Chemistry, 2013, 33(9): 1970-1974.
7. Liu Zhiping; Wei Wanxing*; Zhou Min; Gan Chunfang; Liu Sheng. A new prenylated xanthone from root barks of Cudrania cochinchinsis. Chinese Herbal Medicines, 2013, 5(2): 101-103
8. Zhiping Liu, Wanxing Wei*, Chunfang Gan, Yanmin Huang, Sheng Liu, Min Zhou, Jianguo Cui. Semisynthesis and Cytotoxicity of E-Naringenin Oximes from Naringin. Chin. J. Org. Chem., 2013, 33, 2551-2558.
9. Zhiping Liu, Wanxing Wei*, Min Zhou, Sheng Liu, Chunfang Gan. Isolation, Structure Modification and Cytotoxicity of Benzopyranyl Isiflavones from Cudrania Cochinchinensis Fruits. Chemistry , 2014, 77, 994-997.
10. Zhiping Liu, Min Zhou, Sheng Liu, Chunfang Gan, Wanxing Wei*. Isolation of two benzopyran isoflavones from fruits of Cudrania cochinchinensis and their antitumor activities, Chinese Traditional and Herbal Drugs, 2013, 7, 1734-1739
部分教育论文：
2025年
1. 浅谈美育在中学化学教学中的融合与渗透[J].中学课程资源, 2025,21(1):35-37
2. 美育的功能及在中学化学教学中的融合策略[J].中学理科园地,2025,21(2):14-16
3. 基于“科研导向、教研融合”的有机化学研究生培养模式探索与实践[J].化工设计通讯,2025,51(10):78-7989
4. Mercury技术在化学晶体结构教学中的可视化应用策略[J].中小学实验与装备,2025,35(3):14-17
5. 黑龙江地方特色文化融入中学化学教学的项目式设计——以哈尔滨红肠为例[J].理科考试研究,2025,32(12):71-75
2024年
1. 基于价值、能力、情境的化学高考试题分析[J].基础教育研究,2024(10):64-6678
2. 借助数学思想方法 探析化学解题策略[J].中学生理科应试,2024(9):38-40
3. 价值、能力、情境视角下高考化学工艺流程题分析——以2024年高考化学题为例[J].理科考试研究,2024,31(19):56-60
4. 极限思想在化学教学中的应用——以“溶液配制中的误差分析”为例[J].中小学实验与装备,2024,34(5):17-19
5. 传统工艺视域下高中化学项目式教学设计——以“揭秘丹泉酒的酿造工艺”为例[J].理科考试研究,2024,31(3):49-53
6. 融入非遗文化的高中化学项目式教学——以“地方特色灰水粽制作技艺”为例[J].理科考试研究,2024,31(13):49-53
7. 非遗文化“境脉”下“氧化还原反应复习”主题式教学[J].理科考试研究,2024,31(15):49-53
8. 中国传统文化视角下的中学化学教学设计——以“无机非金属材料”为例[J].中学理科园地,2024,20(2):12-1418
9. 体现地域特色的校本教学设计——以“宁明花山岩画”为例[J].中学化学教学参考,2024(8):72-75
2023年
1. 浅谈大学有机化学开放性实验案例的探索——以2-苯甲酰基苯并呋喃的合成为例[J].四川化工,2023,26(2):57-60
2. 大学有机化学课程教学的高阶思维培养与实践——以“酯化反应”为例[J].南宁师范大学学报（自然科学版）,2023,40(2):187-191
3. 思维可视化在初中化学教学中的应用——以“探究无明显现象反应”为例[J].中学理科园地,2023,19(4):23-2528
4. 新高考化学实验试题分析及教学策略研究[J].基础教育研究,2023(6):29-31
5. 基于“教、学、评”一体化的四线式教学设计——以“硫及其化合物第1课时”的教学为例[J].化学教与学,2023(17):41-45
6. 课程思政与中国传统文化融合的化学教学设计——以“铁的冶炼”为例[J].中学教学参考,2023(35):68-7074
7. 游戏化教学在高中化学中的应用——以“碳酸钠和碳酸氢钠”的教学为例[J].化学教与学,2023(6):16-19
8. 基于“四层四翼”试题情境化的研究和教学建议--以2023年四省联考化学试题为例[J].广西教育,2023(35):41-45
9. 以茶为情境 探究酚的性质[J].中学理科园地,2023,19(3):19-21
10. 借生活情境 析化学之理——以“制作五色糯米饭”教学为例[J].中学课程资源,2023,19(5):15-18
11. 巧用图像表征认识燃料电池[J].教学考试,2023(45):23-28
2022年
1. 中华传统文化融入高中化学教学中的实践研究--以“铁及其化合物”为例[J].化学教与学,2022(9):69-72
2. 渗透营养健康教育的高中化学教学——以“不同水果中维生素C含量的比较”一课为例[J].化学教与学（下半月）,2022(9):59-61
3. 巧用图示思维 落地核心素养——以“酚的性质”教学为例[J].理科考试研究,2022,29(17):57-60
4. 借助古典诗词探析氧化还原反应[J].化学教与学, 2022(11):11-14
5. 高考化学工艺流程题的解题思维模型构建[J].理科考试研究,2022,29(13):56-58
